So I'm putting my wheels back on today and I also am about to clean and lube my chain. I noticed that on the left side we have ticks. What about the right side? How much do I tighten that side? If I'm unclear, I'm talking about the rear axle where you tighten the chain and all that good stuff. On the right side, it's the same exact thing but when you tighten it, it seems to move the location of the axle hole. If I tighten this too much, can't there be some kind of friction or bend on the axle? How will I know if I've tightened it enough or not?

Would a good method be measuring the length of the drive chain adjusters and match it with the other side?

 

They are the adjuster marks, you adjust so that they are the same (in the metal window).This method is notoriously inaccurate, I undo & adjust the nuts exactly the same amount of turns, sure its still inaccurate (to a point) but way better than the standard set up. Don't forget to allow for different tightness in the chain to, that is, find the tightest point in the chain & adjust from there.