I don't have an f2 but I have sat on them and they seem more comfy than my RR. I can do 300 miles in a day without trouble.Like said before take a 15 min break or so each time you fill up and you should be fine. It actually sounds like a kick *** ride! I should do something like that too since I also live in WI.

 

I have done a few 300 mile rides.. and it was mostly twisties. I will sleep like a baby after a day of that. Be sure to drink lots of water in the days leadign up to your ride.